Interferon response gene expression in early stage breast cancer (a) The expression values of genes in the 'interferon response gene set' were extracted from a published expression study of 295 early stage breast cancers from the Netherlands Cancer Institute . Genes and samples are organized by hierarchical clustering. The tumors segregated into two groups defined by high (red) or low (blue) expression levels of 29 genes matching the 'interferon response gene set'. (b) Correlation of interferon response with distant metastasis free and overall survival. Kaplan-Meier curves for the clinical outcomes of indicated tumors exhibiting high (red curve) and low (blue curve) interferon responses are shown.
Buess et al. Genome Biology 2007 8:R191 doi:10.1186/gb-2007-8-9-r191