Table 2

Stem cell markers
Ref.
 Cellular type
 Gene name
 Entrez Gene
 Probe set polled
 Pattern
 Score
 D
[74]
 Differentiated retinal
 309L
 ?
 -
 -
 -
 -


Rho1D4 (rhodopsin)
 ?
 -
 -
 -
 -


D2P4 (rhodopsin)
 ?
 -
 -
 -
 -


CHX10
 Chx10
 1419628_at.A
 Not found
 Not found


PKC
 a
 -
 -
 -
 -


ROM-1
 Rom1
 1448996_at.A
 879
 0.942

Photoreceptor specific homeobox
 Crx
 Crx
 1418705_at.A
 Not found
 Not found

Muller glia
 10E4
 ?
 -
 -
 -
 -
[75]
 Human central nervous system
 CD24-/lo
 CD24a
 1416034_at.A
 573
 0.987
 2


CD34-
 CD34
 1416072_at.A
 72
 0.990
 2


CD45-
 Ptprc
 1422124_a_at.A
 427
 0.987

Human neuronal lineage
 N-CAM
 Ncam1
 1426864_a_at.A
 318
 1.000

Neural
 CD133
 Prom1
 1419700_a_at.A
 573
 0.930
 2

Hematopoietic
 CD133
 Prom1
 1419700_a_at.A
 573
 0.930
 2
[76]
 Proliferating neural
 Ki-67
 Mki67
 1426817_at.A
 8
 0.991
[77]
 Trophoblast
 Cdx2
 Cdx2
 1422074_at.A
 Not found
 Not found

Ectoderm
 Fgf5
 Fgf5
 1438883_at.B
 442
 1.000

Neuroectoderm
 Isl1
 Isl1
 1422720_at.A
 83
 0.931

Pluripotent stem cell
 Nanog
 Nanog
 1429388_at.A
 390
 0.947


Oct3/4
 Pou5f1
 1417945_at.A
 151
 1.000


Rex1
 Zfp42
 1418362_at.A
 547
 0.964

Mesoderm
 Brachyury
 T
 1419304_at.A
 232
 0.938
[78]
 Neural stem cell
 Hu
 ?
 -
 -
 -
 -


Neuralstemmin
 ?
 -
 -
 -
 -


ABCG2
 Abcg2
 1422906_at.A
 Not found
 Not found
 3


LeX/SSEA-1
 Fut4
 1455843_at.B
 771
 0.924


Musashi (Msi1)
 Msi1
 1421409_at.A
 Not found
 Not found
 2


Sox-1
 Sox1
 1438729_at.B
 542
 0.958


Sox-2
 Sox2
 1416967_at.A
 71
 0.986
[79]
 Muscle specific
 MCK (muscle creatine kinase)
 Ckm
 1417614_at.A
 104
 1.000


MHC (myosin heavy chain)
 Myh4
 1427026_at.A
 Not found
 Not found

Myofiber sarcolemma
 Dystrophin
 Dmd
 1417307_at.A
 835
 0.958

Basal lamina
 Laminin
 a
 -
 -
 -
 -

Myogenic lineage
 Myf5
 Myf5
 1420757_at.A
 Not found
 Not found


MyoD
 Myod1
 1418420_at.A
 32
 1.000

Late myogenic lineage
 MRF4
 Myf6
 1419150_at.A
 Not found
 Not found


Myogenin
 Myog
 1419391_at.A
 104
 1.000

Satellite cells
 Pax7
 Pax7
 1452510_at.A
 Not found
 Not found
[80]
 Neural restricted precursors
 MAP2
 Mtap2
 1434194_at.B
 108
 1.000
 2


Beta3 tubulin
 Tubb3
 1415978_at.A
 Not found
 Not found
[81]
 SKP
 Fibronectin
 Fn1
 1426642_at.A
 681
 0.984


GAP43
 Gap43
 1423537_at.A
 363
 0.959


MAP2
 Mtap2
 1434194_At.B
 108
 1.000
 2


Nestin
 Nes
 1449022_at.A
 73
 0.980
 2


p75NTR
 Ngfr
 1421241_at.A
 Not found
 Not found


Vimentin
 Vim
 1450641_at.A
 770
 0.977
[82]
 Hematopoietic stem cell
 BCRP1
 Abcg2
 1422906_at.A
 Not found
 Not found

Epidermal side population
 BCRP1
 Abcg2
 1422906_at.A
 Not found
 Not found
 3


alpha6-integrin
 Itga6
 1422444_at.A
 Not found
 Not found
 2


beta1-integrin
 Itgb1
 1426918_at.A
 13
 0.967
 2


keratin 14
 Krt1-14
 1460347_at.A
 386
 0.983


Sca-1
 Ly6a
 1417185_at.A
 637
 0.929
 2


CD34-
 CD34
 1416072_at.A
 72
 0.990
 2


E-cadherin
 Cdh1
 1448261_at.A
 48
 0.993


Keratin 19
 Krt1-19
 1417156_at.A
 268
 0.989
 2


CD71-
 Tfrc
 1452661_at.A
 845
 0.958
[83]
 Muller glia; retinal
 Gln synthetase
 Glul
 1426235_a_at.A
 573
 0.901

Retinal
 syntaxin
 a
 -
 -
 -
 -


Pax6
 Pax6
 1419271_at.A
 374
 0.960


rhodopsin
 Rho
 1425171_at.A
 Not found

[84]
 Neural
 (NeuN) Neuron specific protein
 ?
 -
 -
 -
 -


Neuron-specific enolase
 Eno2
 1418829_a_at.A
 Not found
 Not found
 -

Osteoblasts
 Alkaline phosphatase
 Akp2
 1423611_at.A
 Not found
 Not found
 -


BMP2
 Bmp2
 1423635_at.A
 Not found
 Not found
 -


BMP4
 Bmp4
 1422912_at.A
 Not found
 Not found
 -


BMP Receptor 1
 Bmpr1a
 1425492_at.A
 581
 0.939



Bmpr1b
 1437312_at.B
 446
 0.917


BMP Receptor 2
 Bmpr2
 1434310_at.B
 602
 0.954


PTH receptor
 Pthr2
 1452129_at.A
 Not found



Type 1 collagen
 a
 -
 -
 -
 -


bone sialoprotein
 Ibsp
 1417484_at.A
 Not found



PTH receptor
 Pthr1
 1417092_at.A
 368
 0.964


RunX-1
 Runx1
 1422865_at.A
 295
 0.982


osteonectin
 Sparc
 1448392_at.A
 581
 1.000


osteopontin
 spp1
 1449254_at.A
 737
 0.996

General stem cell factor receptor
 CD117
 Kit
 1459588_at.B
 243
 0.912

Muscle
 merosin
 Lama2
 1426285_at.A
 799
 0.986

Cartilage related extracellular matrix
 aggrecan
 Agc1
 1449827_at.A
 Not found
 Not found
 -


collagen II
 a
 -
 -
 -
 -


collagen IV
 a
 -
 -
 -
 -


PRELP
 Prelp
 1416322_at.A
 231
 0.958

Adipose derived stem cell
 CD49d+
 Itga4
 1421194_at.A
 Not found
 Not found
 -


CD106-
 ?
 -
 -
 -
 -
[85]
 Mammary stem cell
 Bmi-1
 Bmi1
 Not on array
 -
 -
 -


p21
 Cdkn1a
 1424638_at.A
 400
 0.967


CD49f
 Itga6
 1422444_at.A
 Not found
 Not found
 2


Cytokeratin 19
 Krt1-19
 1417156_at.A
 268
 0.989
 2


Sca-1
 Ly6a
 1417185_at.A
 637
 0.930
 2


Musashi (Msi1)
 Msi1
 1421409_at.A
 Not found
 Not found
 2


Cytokeratin 5/6
 ?
 -
 -
 -
 -
[86]
 Neural enrichment
 CD24
 CD24a
 1416034_at.A
 573
 0.990
 2

Skin
 CD29
 Itgb1
 1426918_at.A
 13
 0.970
 2
[87]
 Neural
 GFAP
 Gfap
 1426508_at.A
 249
 0.924


Neurofilament
 Nefl
 1426255_at.A
 151
 0.935


Nestin
 Nes
 1449022_at.A
 73
 0.980
 2

Photoreceptors
 Recoverin
 Rcvrn
 1450215_at.A
 Not found
 Not found
 -

Epithelial lineage
 Cytokeratin (904-clone 34betaB4?)
 a
 -
 -
 -
 -


CK18
 Krt1-18
 1448169_at.A
 83
 0.917


AE1
 Slc4a1
 1416464_at.A
 41
 1.000
[88]
 Epithelial lineage
 AE3
 Slc4a3
 1418485_at.A
 391
 0.931

Note that some markers may be included in multiple rows of the table (as many as indicated in the right-most column), because a number of genes have been identified as markers of more than one cell type (for example, Abcg2 for hematopoietic and neural cells [78,82], or Nestin for neural and skin-derived precursors [SKPs] [81,87]). Some of the markers could not be assigned to an Entrez gene either because the marker name was ambiguous (indicated by 'a') or was absent from the database of gene names (indicated by '?'). Patterns can be examined online via the web server [21]. All patterns for which a polled probe set is a marker can also be examined at the web server. Note that the chip containing the probe set is indicated by '.A' or '.B' appended to the identifier, because some probe sets are included in both the MOE430A and the MOE430B chips.

Krzyzanowski and Andrade-Navarro Genome Biology 2007 8:R193   doi:10.1186/gb-2007-8-9-r193

Open Data