Table 2

Stem cell markers

Ref.

Cellular type

Gene name

Entrez Gene

Probe set polled

Pattern

Score

D


[74]

Differentiated retinal

309L

?

-

-

-

-

Rho1D4 (rhodopsin)

?

-

-

-

-

D2P4 (rhodopsin)

?

-

-

-

-

CHX10

Chx10

1419628_at.A

Not found

Not found

PKC

a

-

-

-

-

ROM-1

Rom1

1448996_at.A

879

0.942

Photoreceptor specific homeobox

Crx

Crx

1418705_at.A

Not found

Not found

Muller glia

10E4

?

-

-

-

-

[75]

Human central nervous system

CD24-/lo

CD24a

1416034_at.A

573

0.987

2

CD34-

CD34

1416072_at.A

72

0.990

2

CD45-

Ptprc

1422124_a_at.A

427

0.987

Human neuronal lineage

N-CAM

Ncam1

1426864_a_at.A

318

1.000

Neural

CD133

Prom1

1419700_a_at.A

573

0.930

2

Hematopoietic

CD133

Prom1

1419700_a_at.A

573

0.930

2

[76]

Proliferating neural

Ki-67

Mki67

1426817_at.A

8

0.991

[77]

Trophoblast

Cdx2

Cdx2

1422074_at.A

Not found

Not found

Ectoderm

Fgf5

Fgf5

1438883_at.B

442

1.000

Neuroectoderm

Isl1

Isl1

1422720_at.A

83

0.931

Pluripotent stem cell

Nanog

Nanog

1429388_at.A

390

0.947

Oct3/4

Pou5f1

1417945_at.A

151

1.000

Rex1

Zfp42

1418362_at.A

547

0.964

Mesoderm

Brachyury

T

1419304_at.A

232

0.938

[78]

Neural stem cell

Hu

?

-

-

-

-

Neuralstemmin

?

-

-

-

-

ABCG2

Abcg2

1422906_at.A

Not found

Not found

3

LeX/SSEA-1

Fut4

1455843_at.B

771

0.924

Musashi (Msi1)

Msi1

1421409_at.A

Not found

Not found

2

Sox-1

Sox1

1438729_at.B

542

0.958

Sox-2

Sox2

1416967_at.A

71

0.986

[79]

Muscle specific

MCK (muscle creatine kinase)

Ckm

1417614_at.A

104

1.000

MHC (myosin heavy chain)

Myh4

1427026_at.A

Not found

Not found

Myofiber sarcolemma

Dystrophin

Dmd

1417307_at.A

835

0.958

Basal lamina

Laminin

a

-

-

-

-

Myogenic lineage

Myf5

Myf5

1420757_at.A

Not found

Not found

MyoD

Myod1

1418420_at.A

32

1.000

Late myogenic lineage

MRF4

Myf6

1419150_at.A

Not found

Not found

Myogenin

Myog

1419391_at.A

104

1.000

Satellite cells

Pax7

Pax7

1452510_at.A

Not found

Not found

[80]

Neural restricted precursors

MAP2

Mtap2

1434194_at.B

108

1.000

2

Beta3 tubulin

Tubb3

1415978_at.A

Not found

Not found

[81]

SKP

Fibronectin

Fn1

1426642_at.A

681

0.984

GAP43

Gap43

1423537_at.A

363

0.959

MAP2

Mtap2

1434194_At.B

108

1.000

2

Nestin

Nes

1449022_at.A

73

0.980

2

p75NTR

Ngfr

1421241_at.A

Not found

Not found

Vimentin

Vim

1450641_at.A

770

0.977

[82]

Hematopoietic stem cell

BCRP1

Abcg2

1422906_at.A

Not found

Not found

Epidermal side population

BCRP1

Abcg2

1422906_at.A

Not found

Not found

3

alpha6-integrin

Itga6

1422444_at.A

Not found

Not found

2

beta1-integrin

Itgb1

1426918_at.A

13

0.967

2

keratin 14

Krt1-14

1460347_at.A

386

0.983

Sca-1

Ly6a

1417185_at.A

637

0.929

2

CD34-

CD34

1416072_at.A

72

0.990

2

E-cadherin

Cdh1

1448261_at.A

48

0.993

Keratin 19

Krt1-19

1417156_at.A

268

0.989

2

CD71-

Tfrc

1452661_at.A

845

0.958

[83]

Muller glia; retinal

Gln synthetase

Glul

1426235_a_at.A

573

0.901

Retinal

syntaxin

a

-

-

-

-

Pax6

Pax6

1419271_at.A

374

0.960

rhodopsin

Rho

1425171_at.A

Not found

[84]

Neural

(NeuN) Neuron specific protein

?

-

-

-

-

Neuron-specific enolase

Eno2

1418829_a_at.A

Not found

Not found

-

Osteoblasts

Alkaline phosphatase

Akp2

1423611_at.A

Not found

Not found

-

BMP2

Bmp2

1423635_at.A

Not found

Not found

-

BMP4

Bmp4

1422912_at.A

Not found

Not found

-

BMP Receptor 1

Bmpr1a

1425492_at.A

581

0.939

Bmpr1b

1437312_at.B

446

0.917

BMP Receptor 2

Bmpr2

1434310_at.B

602

0.954

PTH receptor

Pthr2

1452129_at.A

Not found

Type 1 collagen

a

-

-

-

-

bone sialoprotein

Ibsp

1417484_at.A

Not found

PTH receptor

Pthr1

1417092_at.A

368

0.964

RunX-1

Runx1

1422865_at.A

295

0.982

osteonectin

Sparc

1448392_at.A

581

1.000

osteopontin

spp1

1449254_at.A

737

0.996

General stem cell factor receptor

CD117

Kit

1459588_at.B

243

0.912

Muscle

merosin

Lama2

1426285_at.A

799

0.986

Cartilage related extracellular matrix

aggrecan

Agc1

1449827_at.A

Not found

Not found

-

collagen II

a

-

-

-

-

collagen IV

a

-

-

-

-

PRELP

Prelp

1416322_at.A

231

0.958

Adipose derived stem cell

CD49d+

Itga4

1421194_at.A

Not found

Not found

-

CD106-

?

-

-

-

-

[85]

Mammary stem cell

Bmi-1

Bmi1

Not on array

-

-

-

p21

Cdkn1a

1424638_at.A

400

0.967

CD49f

Itga6

1422444_at.A

Not found

Not found

2

Cytokeratin 19

Krt1-19

1417156_at.A

268

0.989

2

Sca-1

Ly6a

1417185_at.A

637

0.930

2

Musashi (Msi1)

Msi1

1421409_at.A

Not found

Not found

2

Cytokeratin 5/6

?

-

-

-

-

[86]

Neural enrichment

CD24

CD24a

1416034_at.A

573

0.990

2

Skin

CD29

Itgb1

1426918_at.A

13

0.970

2

[87]

Neural

GFAP

Gfap

1426508_at.A

249

0.924

Neurofilament

Nefl

1426255_at.A

151

0.935

Nestin

Nes

1449022_at.A

73

0.980

2

Photoreceptors

Recoverin

Rcvrn

1450215_at.A

Not found

Not found

-

Epithelial lineage

Cytokeratin (904-clone 34betaB4?)

a

-

-

-

-

CK18

Krt1-18

1448169_at.A

83

0.917

AE1

Slc4a1

1416464_at.A

41

1.000

[88]

Epithelial lineage

AE3

Slc4a3

1418485_at.A

391

0.931


Note that some markers may be included in multiple rows of the table (as many as indicated in the right-most column), because a number of genes have been identified as markers of more than one cell type (for example, Abcg2 for hematopoietic and neural cells [78,82], or Nestin for neural and skin-derived precursors [SKPs] [81,87]). Some of the markers could not be assigned to an Entrez gene either because the marker name was ambiguous (indicated by 'a') or was absent from the database of gene names (indicated by '?'). Patterns can be examined online via the web server [21]. All patterns for which a polled probe set is a marker can also be examined at the web server. Note that the chip containing the probe set is indicated by '.A' or '.B' appended to the identifier, because some probe sets are included in both the MOE430A and the MOE430B chips.

Krzyzanowski and Andrade-Navarro Genome Biology 2007 8:R193   doi:10.1186/gb-2007-8-9-r193

Open Data