Table 3 |
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|
Gene Ontology terms of marker sets |
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| All |
Selected set |
High in differentiated |
GO |
GOID |
||
|
|
||||||
| N1 |
N2 |
P2 |
N3 |
P3 |
||
| 7,478 |
4,449 |
222 |
Total |
|||
| 976 |
727 |
2.85 × 10-22 |
81 |
1.60 × 10-16 |
Extracellular region |
GO:0005576 |
| 169 |
131 |
0.001824 |
17 |
0.009344 |
Extracellular matrix |
GO:0031012 |
| 72 |
57 |
>1 |
12 |
0.00106 |
Enzyme inhibitor activity |
GO:0004857 |
| 2,061 |
1,390 |
8.07 × 10-15 |
73 |
>1 |
Membrane |
GO:0016020 |
| 865 |
618 |
2.44 × 10-11 |
25 |
>1 |
Signal transducer activity |
GO:0004871 |
| 587 |
421 |
4.00 × 10-7 |
15 |
>1 |
Receptor activity |
GO:0004872 |
| 925 |
637 |
8.62 × 10-7 |
43 |
>1 |
Multicellular organismal development |
GO:0007275 |
| 312 |
235 |
6.34 × 10-6 |
16 |
>1 |
Defense response |
GO:0006952 |
| 911 |
614 |
0.000403 |
32 |
>1 |
Cell communication |
GO:0007154 |
| 270 |
201 |
0.000485 |
17 |
>1 |
Cell adhesion |
GO:0007155 |
| 436 |
310 |
0.000596 |
18 |
>1 |
Organ development |
GO:0048513 |
|
|
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|
Column labels are as follows: N1 is the number of genes for a Gene Ontology (GO) category in the unselected marker set; N2 and P2 are the number of genes and P value for the smaller marker set; N3 and P3 are the number of genes and P value for the markers highly expressed in differentiated stem cells; GO is the description of the GO term; and GOID is the GO identifier. P values are computed using the 'All' set of markers as background. GO terms displayed if they represent more than ten genes have at least one associated P value below 0.01 and do not overlap more than 80% with another displayed term. |
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|
Krzyzanowski and Andrade-Navarro Genome Biology 2007 8:R193 doi:10.1186/gb-2007-8-9-r193 |
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