Table 3

Gene Ontology terms of marker sets

All

Selected set

High in differentiated

GO

GOID


N1

N2

P2

N3

P3

7,478

4,449

222

Total

976

727

2.85 × 10-22

81

1.60 × 10-16

Extracellular region

GO:0005576

169

131

0.001824

17

0.009344

Extracellular matrix

GO:0031012

72

57

>1

12

0.00106

Enzyme inhibitor activity

GO:0004857

2,061

1,390

8.07 × 10-15

73

>1

Membrane

GO:0016020

865

618

2.44 × 10-11

25

>1

Signal transducer activity

GO:0004871

587

421

4.00 × 10-7

15

>1

Receptor activity

GO:0004872

925

637

8.62 × 10-7

43

>1

Multicellular organismal development

GO:0007275

312

235

6.34 × 10-6

16

>1

Defense response

GO:0006952

911

614

0.000403

32

>1

Cell communication

GO:0007154

270

201

0.000485

17

>1

Cell adhesion

GO:0007155

436

310

0.000596

18

>1

Organ development

GO:0048513


Column labels are as follows: N1 is the number of genes for a Gene Ontology (GO) category in the unselected marker set; N2 and P2 are the number of genes and P value for the smaller marker set; N3 and P3 are the number of genes and P value for the markers highly expressed in differentiated stem cells; GO is the description of the GO term; and GOID is the GO identifier. P values are computed using the 'All' set of markers as background. GO terms displayed if they represent more than ten genes have at least one associated P value below 0.01 and do not overlap more than 80% with another displayed term.

Krzyzanowski and Andrade-Navarro Genome Biology 2007 8:R193   doi:10.1186/gb-2007-8-9-r193

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