Table 1 |
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Common response genes in the pathogen-shared host response |
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Microarray data |
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Set of three datasets (E. f, E. c and P. l) |
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BRB-ArrayTools |
MAANOVA |
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Fold change (infected/control) |
(Infected/control) |
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Sequence name |
Gene name |
Brief description |
E. f |
E. c |
P. l |
p value |
p value |
|
|
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Up-regulated genes |
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|
T28H10.3 |
Asparaginyl peptidases |
1.67 |
1.29 |
2.43 |
1.67 |
3.47E-05 |
1.17E-02 |
|
|
Y39B6A.20 |
asp-1 |
Aspartyl protease |
3.54 |
1.80 |
2.17 |
2.09 |
2.06E-05 |
<1.00E-07 |
|
H22K11.1 |
asp-3 |
Aspartyl protease |
2.59 |
1.47 |
2.29 |
1.96 |
4.80E-06 |
<1.00E-07 |
|
F21F8.3 |
asp-5 |
Aspartyl protease |
2.53 |
2.48 |
1.86 |
2.06 |
2.83E-05 |
<1.00E-07 |
|
F21F8.7 |
asp-6 |
Aspartyl protease |
2.96 |
1.89 |
1.88 |
- |
- |
<1.00E-07 |
|
Y39B6A.24 |
Aspartyl protease |
1.84 |
1.40 |
1.62 |
1.59 |
1.21E-05 |
<1.00E-07 |
|
|
F44A2.3 |
BPI/LBP/CETP family protein |
3.43 |
1.73 |
2.03 |
2.29 |
5.00E-07 |
2.35E-03 |
|
|
F35C5.6 |
clec-63 |
C-lectin |
1.95 |
2.05 |
2.62 |
2.23 |
1.00E-07 |
<1.00E-07 |
|
Y37E3.15a |
npp-13 |
Cullin |
1.89 |
- |
1.57 |
1.62 |
5.30E-06 |
- |
|
T21H3.1 |
Lipase |
1.38 |
1.99 |
1.89 |
1.85 |
8.00E-07 |
<1.00E-07 |
|
|
Y22F5A.4 |
lys-1 |
Lysozyme |
1.33 |
1.30 |
1.81 |
- |
- |
4.82E-02 |
|
F59A1.6 |
Saposin A |
1.92 |
1.82 |
1.92 |
1.78 |
2.60E-05 |
- |
|
|
W02D7.8 |
Uncharacterized, nematode-specific |
- |
1.46 |
2.20 |
1.64 |
3.49E-05 |
- |
|
|
ZK1320.3 |
Uncharacterized, nematode-specific |
1.51 |
1.85 |
1.63 |
1.54 |
5.70E-06 |
- |
|
|
F28B4.3 |
von Willebrand factor type A |
2.28 |
- |
2.09 |
- |
- |
4.14E-02 |
|
|
K06G5.1 |
von Willebrand factor type A |
1.51 |
1.27 |
1.91 |
- |
- |
2.55E-02 |
|
|
Down-regulated genes |
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C55B7.4a |
acdh-1 |
Acyl-CoA dehydrogenase |
0.33 |
0.47 |
0.35 |
0.35 |
<1.00E-07 |
<1.00E-07 |
|
C17C3.12b |
acdh-2 |
Acyl-CoA dehydrogenase |
0.59 |
0.54 |
0.52 |
0.54 |
1.00E-07 |
<1.00E-07 |
|
Y38F1A.6 |
Alcohol dehydrogenase, class IV |
0.59 |
0.54 |
0.53 |
0.55 |
8.00E-07 |
<1.00E-07 |
|
|
T05G5.6 |
ech-6 |
Enoyl-CoA hydratase |
0.55 |
0.62 |
0.49 |
0.62 |
3.00E-06 |
<1.00E-07 |
|
K02F2.2 |
S-adenosylhomocysteine hydrolase |
0.67 |
0.69 |
- |
0.70 |
8.20E-06 |
4.69E-03 |
|
|
F54D11.1 |
pmt-2 |
SAM-dependent methyltransferases |
0.67 |
0.68 |
0.66 |
0.69 |
1.13E-05 |
- |
|
|
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E. c, E. carotovora; E. f, E. faecalis; P. l, P. luminescens. |
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|
Wong et al. Genome Biology 2007 8:R194 doi:10.1186/gb-2007-8-9-r194 |
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