Identification of novel regulatory factor X (RFX) target genes by comparative genomics in Drosophila species

Anne Laurençon¹^,2 , Raphaëlle Dubruille¹^,2^,3 , Evgeni Efimenko⁴ , Guillaume Grenier¹^,2 , Ryan Bissett¹^,2^,5 , Elisabeth Cortier¹^,2 , Vivien Rolland¹^,2 , Peter Swoboda⁴ and Bénédicte Durand¹^,2

¹Université de Lyon, Lyon, F-69003, France

²Université Lyon 1, CNRS, UMR5534, Centre de Génétique Moléculaire et Cellulaire, Villeurbanne, F-69622, France

³University of Massachusetts Medical School, Department of Neurobiology, Worcester, MA 01605, USA

⁴Karolinska Institute, Department of Biosciences and Nutrition, Södertörn University College, School of Life Sciences, S-14189 Huddinge, Sweden

⁵University of Glasgow, Glasgow Biomedical Research Centre, Wellcome Centre for Molecular Parasitology and Infection and Immunity, Glasgow G12 8TA, UK

author email corresponding author email

Genome Biology 2007, 8:R195doi:10.1186/gb-2007-8-9-r195


Published:	17 September 2007

Subject areas: Development, Molecular biology, Genetics, Genome studies

Additional files

Additional data file 1:

Our X-box search across D. melanogaster and D. pseudoobscura species identified 412 genes with a conserved X-box both in sequence and distance upstream of the ATG of homologous genes between the two fly genomes.

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Additional data file 2:

Genes presented in this table are homologous to proteins identified as putative or confirmed ciliary or basal body components. They are sorted as follows: a first group of genes with annotated molecular functions, a second group of genes for which homologs in vertebrates have been reported, a third group of genes with no vertebrate homolog. Each category is sorted by the number of studies reporting each gene or its homolog.

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Additional data file 3:

Number of Drosophila genes homologous to ciliary genes identified in previously published studies.

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