Table 3

Eighty-three genes selected for a conserved X-box between D. melanogaster and D. pseudoobscura

Source [reference]


CG# release 3.2.1

Rfx target fold reduction

Flybase gene name

Known protein function

Annotated predictive function

[12]

[11]

[14]

[13]

[10]

[15]

[36]

[37]

[45]

[44]

[59]

DCBB

Ciliome database

Ciliary proteome database

Human homologs


1126

95

CG1126

BBS5

ν

ν

ν

ν

ν

ν

ν

NP_689597

2321

-

CG2321

-

NP_060350.1

2691

-

CG2691

-

NP_055994.1

3259

iv

CG3259

MIP_T3

ν

ν

ν

ν

ν

ν

ν

ν

ν

NP_056465

3344

-

CG3344

Serine carboxypeptidase

NP_067639.1

3603

-

CG3603

Rhodopsin-like receptor

ν

NP_055049.1

3723

3

Dhc93AB

DNAH9

ATPase activity, coupled

ν

ν

ν

ν

ν

ν

ν

NP_001363

3769

63

CG3769

xbx1/D2LIC

ν

ν

ν

ν

ν

ν

NP_057092

4135

-

beat-IIb

IgSF protein, axon guidance

1 to many

4314

-

st

scarlet

ATPase

1 to many

4536

6

iav

TRPV4

ν

NP_067638.3

4857

-

CG4857

-

-

4984

-

CG4984

-

NP_114102.2

5148

-

CG5148

-

-

5155

Neg

CG5155

-

Binding

ν

ν

ν

ν

NP_060546

5599

-

CG5599

Acetyltransferase

ν

ν

NP_001909

6054

Neg

Su(fu)

Su(fu)

Kinase inhibitor

NP_057253.2

6121

Neg

Tip60

Histone acetyltransferase

ν

NP_874369.1

6129

6/iv

CG6129

rootletin

ν

ν

ν

ν

NP_055490

6405

-

CG6405

-

XP_936274.2

6665

-

CG6665

-

NP_056264.1

6696

-

CG6696

Meprin A/proteolysis

ν

NP_005916

7104

-

Spz3

-

7669

-

CG7669

ν

ν

NP_002815.3

7754

-

iotaTry

Trypsin

1 to many

8344

-

RpIII128

RNA polIIIb

ν

NP_060552.3

8362

Neg

nmdynD7

Nucleoside diphosphate kinase

ν

ν

ν

ν

ν

ν

ν

ν

ν

ν

NP_037462

8853

23

CG8853

IFT55/Hippi

ν

ν

ν

ν

ν

ν

ν

ν

ν

ν

NP_060480

8971

-

fh

frataxin like

NP_000135.2

9035

-

Tapdelta

Signal sequence binding

NP_006271.1

9227

iv

tectonic

Tectonic

ν

ν

ν

ν

ν

ν

ν

NP_085055

9298

-

CG9298

Synbindin

NP_057230.1

9363

-

CG9363

Glutathione transferase zeta

NP_665877.1

9467

-

CG9467

V-gated K channel complex

NP_057205.2

9689

-

CG9689

-

-

9764

-

yrt

yurt

Cytoskeletal protein binding

NP_060894.2

10035

-

CG10035

-

-

10068

-

CG10068

-

NP_714913.1

10143

-

Adgf-E

Adenosine deaminase

NP_803124.1

10601

-

mirr

Protein binding

ν

NP_077311

10859

-

CG10859

DIC

Motor activity

NP_075462

11015

-

CG11015

COX5B

Cytochrome-c oxidase

ν

NP_001853

11164

-

CG11164

-

NP_078846.1

11356

-

CG11356

ARL13B

GTP binding

NP_878899

11426

-

CG11426

Lipid metabolism

1 to many

11438

-

CG11438

G protein coupled pathway

NP_795714.1

11529

-

CG11529

Chymotrypsin activity

NP_005037.1

11983

-

CG11983

-

-

12020

-

CG12020

-

Heat shock protein binding

ν

ν

ν

NP_705842.2

13125

5

CG13125

LRR

ν

ν

ν

ν

ν

ν

ν

NP_112584

13202

-

CG13202

-

-

13216

-

CG13216

-

-

13251

-

CG13251

-

NP_001012524.1

13271

-

Ugt36Bb

Glucuronosyltransferase

1 to many

13415

2

Cby

Chibby

NP_056188.1

13432

Neg

l(2)05510

-

-

13809

172/iv

osm-1

IFT172/wim

ν

ν

ν

ν

ν

ν

ν

ν

ν

NP_056477

14079

-

CG14079

-

NP_061946.1

14127

Neg

CG14127

-

ν

ν

ν

ν

NP_659482

14313

-

CG14313

-

-

14430

-

CG14430

-

-

14661

-

CG14661

-

-

14791

Neg

Rab27

GTP binding

ν

ν

ν

ν

NP_004571

15148

124

btv

DNCH2

ATPase activity, coupled

ν

ν

ν

ν

ν

ν

NP_001073932

15161

207

CG15161

IFT46/dyf-6

ν

ν

ν

ν

ν

ν

ν

ν

NP_064538

15564

-

CG15564

-

-

15878

-

CG15878

-

-

17150

2

CG17150

DNAH3

Motor activity

ν

ν

ν

NP_060009

17259

-

CG17259

Seryl trna synthetase

ν

NP_006504.2

17284

-

Obp93a

Odorant binding

-

17785

Neg

Golgin84

NP_005104.2

18432

-

CG18432

NP_001073991.1

18584

-

CG18584

UNC84

NP_056189.1

18869

-

CG18869

UDP glycosyl transferase

-

30021

-

skf

Guanylate kinase

NP_775767.2

30441

2.8

CG30441

IFT20

ν

ν

ν

ν

ν

ν

NP_777547.1

31036

4/iv

CG31036

-

-

31127

-

Wsck

Protein-tyrosine kinase

NP_005223.3

31257

-

CG31257

-

-

31321

-

CG31321

-

NP_542400.2

31640

-

CG31640

-

Protein-tyrosine kinase

NP_001014796.1

31824

-

CG31824

-

Trypsin

-

33038

Neg

CG8433

exostosin2

NP_056499.2


Listing established with the restricted GYTRYYN{1-3}RRHRAC X-box consensus. Neg, invariant expression in dRfx deficient background compared to wt; iv, in vivo confirmation of reporter construct down regulation in dRfx deficient background compared to wild type. The presence of a gene in other published studies is noted as ν.

Laurençon et al. Genome Biology 2007 8:R195   doi:10.1186/gb-2007-8-9-r195

Open Data