Schematic diagram of the domain structures of representative members of the 35 myosin classes. The sequence name of the representative member is given in the motor domain of the respective myosin. A color key to the domain names and symbols is given on the right except for the myosin domain, which is colored in blue. The abbreviations for the domains are: C1, protein kinase C conserved region 1; CBS, cystathionine-beta-synthase; Cyt-b5, cytochrome b5-like Heme/Steroid binding domain; DIL, dilute; FERM, band 4.1, ezrin, radixin, and moesin; FYVE, zinc finger in Fab1, YOTB/ZK632.12, Vac1, and EEA1; IQ motif, isoleucine-glutamine motif; MyTH1, myosin tail homology 1; MyTH4, myosin tail homology 4; PB1, Phox and Bem1p domain; PDZ, PDZ domain; PH, pleckstrin homology; Pkinase, protein kinase domain; PX, phox domain; RA, Ras association (RalGDS/AF-6) domain; RCC1, regulator of chromosome condensation; RhoGAP, Rho GTPase-activating protein; SH2, src homology 2; SH3, src homology 3; UBA, ubiquitin associated domain; WD40, WD (tryptophan-aspartate) or beta-transducin repeats.
Odronitz and Kollmar Genome Biology 2007 8:R196 doi:10.1186/gb-2007-8-9-r196