Expression of SAA genes. (a) All four isotype genes were dose-dependently increased with increasing dietary cholesterol exposure. *Significant compared to Con, P < 0.01. (b) Plasma SAA levels in response to increasing doses of dietary cholesterol. Female E3L animals (n ≥ 7/condition) were fed the Con diet supplemented with increasing concentrations of cholesterol for 10 weeks. *P < 0.05 versus 0% w/w cholesterol control group. (c) Plasma SAA levels in the HC diet (1% w/w cholesterol) fed female E3L animals (n = 8) over time. *P < 0.05 versus t = 0.
Kleemann et al. Genome Biology 2007 8:R200 doi:10.1186/gb-2007-8-9-r200