Table 2

EASE analysis results

System
Category
EASE score
Permutation P value
Reversibility group

GO molecular function
Oxidoreductase activity
8.49E-08
1.00E-03
Rapidly reversible genes
GO molecular function
Electron transporter activity
4.60E-06
1.00E-03
Rapidly reversible genes
GenMAPP pathway
Homo sapienspentose phosphate pathway
8.59E-06
1.00E-03
Rapidly reversible genes
GO molecular function
Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
5.73E-05
2.00E-03
Rapidly reversible genes
GO molecular function
Oxidoreductase activity, acting on CH-OH group of donors
7.59E-05
2.00E-03
Rapidly reversible genes
KEGG Pathway
Carbohydrate metabolism - Homo sapiens
1.71E-04
4.00E-03
Rapidly reversible genes
Chromosomal location
16q13
2.02E-03
1.00E-03
Slowly reversible and irreversible genes

EASE was used to identify GO molecular function categories, KEGG pathways, GenMAPP pathways, and chromosomal locations over-represented (Permutation P ≤ 0.01) among genes designated as slowly reversible and irreversible or rapidly reversible compared to all annotated genes on the Affymetrix U133A microarray.

Beane et al. Genome Biology 2007 8:R201   doi:10.1186/gb-2007-8-9-r201

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