Table 2

EASE analysis results

System

Category

EASE score

Permutation P value

Reversibility group


GO molecular function

Oxidoreductase activity

8.49E-08

1.00E-03

Rapidly reversible genes

GO molecular function

Electron transporter activity

4.60E-06

1.00E-03

Rapidly reversible genes

GenMAPP pathway

Homo sapienspentose phosphate pathway

8.59E-06

1.00E-03

Rapidly reversible genes

GO molecular function

Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

5.73E-05

2.00E-03

Rapidly reversible genes

GO molecular function

Oxidoreductase activity, acting on CH-OH group of donors

7.59E-05

2.00E-03

Rapidly reversible genes

KEGG Pathway

Carbohydrate metabolism - Homo sapiens

1.71E-04

4.00E-03

Rapidly reversible genes

Chromosomal location

16q13

2.02E-03

1.00E-03

Slowly reversible and irreversible genes


EASE was used to identify GO molecular function categories, KEGG pathways, GenMAPP pathways, and chromosomal locations over-represented (Permutation P ≤ 0.01) among genes designated as slowly reversible and irreversible or rapidly reversible compared to all annotated genes on the Affymetrix U133A microarray.

Beane et al. Genome Biology 2007 8:R201   doi:10.1186/gb-2007-8-9-r201

Open Data