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This article is part of the supplement: Transposons in vertebrate functional genomics

Review

Transposable elements and the dynamic somatic genome

Lara S Collier* and David A Largaespada

Author Affiliations

The Department of Genetics, Cell Biology and Development, The Cancer Center, The University of Minnesota Twin Cities, Church St SE, Minneapolis, Minnesota 55455, USA

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Genome Biology 2007, 8(Suppl 1):S5  doi:10.1186/gb-2007-8-s1-s5

Published: 31 October 2007

Abstract

Although alterations in the genomes of somatic cells cannot be passed on to future generations, they can have beneficial or detrimental effects on the host organism, depending on the context in which they occur. This review outlines the ways in which transposable elements have important consequences for somatic cell genomes.