Table 1

Vertebrate HCNE terminology disambiguation

Abbreviation
Term
Early reference
Definition

UCR
Ultraconserved region
[26]
≥200 bp 100% conserved between human and mouse


[5]
Nontranscribed, ≥50 bp ≥95% conserved between human and mouse, and at least partially aligned to fugu
UCE
Ultraconserved element
[89]
≥100 bp 100% conserved between human and mouse
CNS
Conserved noncoding sequence
[90]
Nongenic, human:mouse, >100 bp and with ≥70% identity
CNE
Conserved noncoding element
[6]
Nontranscribed, >100 bp human:fugu alignments with MegaBlast
HCNR
Highly conserved noncoding region
[7]
Visual inspection of mouse: Xenopus:zebrafish alignments


[91]
Same as [5]
HCNE
Highly conserved noncoding element
[28]
Windows ≥50 bp that do not overlap coding regions and for which the probability of being under purifying selection, given the conservation score, is ≥95%
CNC
Conserved noncoding region (?)
[38]

CNG
Conserved nongenic sequence
[92]
Nontranscribed, human:mouse BLAST with an e-value < 10-20 and similarity ≥98%
HCE
Highly conserved element
[46]
UCE from Bejerano et al. [26] + UCR from Sandelin et al. [5] + UCR from Sandelin et al. [5] + CNE from Woolfe et al. [6]

Kikuta et al. Genome Biology 2007 8(Suppl 1):S4   doi:10.1186/gb-2007-8-s1-s4