Email updates

Keep up to date with the latest news and content from Genome Biology and BioMed Central.

Minireview

Deciphering histone 2A deubiquitination

Michael J Clague*, Judy M Coulson and Sylvie Urbé*

Author Affiliations

Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, Crown St, Liverpool L69 3BX, UK

For all author emails, please log on.

Genome Biology 2008, 9:202  doi:10.1186/gb-2008-9-1-202

Published: 23 January 2008

Abstract

Three recent papers have identified distinct enzymes that can remove ubiquitin from mammalian histone 2A (H2A). Functions in transcriptional activation, DNA repair and control of the cell cycle have been proposed for these enzymes.