Genome Biology
Volume 9
Issue 1 |
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MinireviewYeast Polo-like kinase substrates are nailed with the right toolsVincent Archambault  and David M Glover Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK  author email corresponding author email
Genome Biology 2008,
9:203doi:10.1186/gb-2008-9-1-203
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| Published: |
30 January 2008 |
Subject areas: Biochemistry and structural biology, Bioinformatics, Cell biology, Methods Abstract
A platform has been built combining chemical genetics and bioinformatics to screen the proteome for physiological substrates of the Polo-like kinase in budding yeast. A novel role for this kinase in regulating the mitotic spindle is revealed. | 
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