Software
MetaReg: a platform for modeling, analysis and visualization of biological systems using large-scale experimental data
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* Corresponding author: Ron Shamir rshamir@tau.ac.il
- † Equal contributors
1 School of Computer Science, Tel Aviv University, Tel Aviv 69978, Israel
2 Computational Molecular Biology Department, Max Planck Institute for Molecular Genetics, Ihnestrasse 73, D-14195 Berlin, Germany
Genome Biology 2008, 9:R1 doi:10.1186/gb-2008-9-1-r1
Published: 2 January 2008Abstract
MetaReg http://acgt.cs.tau.ac.il/metareg/application.html webcite is a computational tool that models cellular networks and integrates experimental results with such models. MetaReg represents established knowledge about a biological system, available today mostly in informal form in the literature, as probabilistic network models with underlying combinatorial regulatory logic. MetaReg enables contrasting predictions with measurements, model improvements and studying what-if scenarios. By summarizing prior knowledge and providing visual and computational aids, it helps the expert explore and understand her system better.