Figure 5.

Phylogenetic analysis of Eri-1-like exonucleases. The neighbor-joining tree is based on the alignment of the exonuclease domain. Eri-1-like nucleases cluster into three subclasses: Eri-1/3'Exo, Snipper, and Pint1. Tribolium and Drosophila have only Snipper-type nucleases. One human and three sea urchin (Strongylocentrotus purpuratus) proteins are represented by NCBI accession numbers.