GO Biological Process enriched themes and their interaction map, illustrating the transcriptomic signature of WAT in obese subjects three months after gastric bypass. (a,b) Functional themes, represented by enriched annotation categories of GO Biological Process (a), were correlated in an interaction network after quantifying their proximity based on the expression similarity of their annotated genes (b). Continuous lines indicate the strongest interactions superior to the upper quartile of their distribution, while dashed lines depict medium strength interactions superior to the median of the distribution but inferior to its upper quartile. (c) A close-up view of the two most important functional interaction modules.
Henegar et al. Genome Biology 2008 9:R14 doi:10.1186/gb-2008-9-1-r14