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Robbins SH
Walzer T
Dembélé D
Thibault C
Defays A
Bessou G
Xu H
Vivier E
Sellars ML
Pierre P
Sharp FR
Chan S
Kastner P
Dalod M

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Robbins SH
Walzer T
Dembélé D
Thibault C
Defays A
Bessou G
Xu H
Vivier E
Sellars ML
Pierre P
Sharp FR
Chan S
Kastner P
Dalod M
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Research

Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

Scott H Robbins¹^,2^,3^,10 , Thierry Walzer¹^,2^,3 , Doulaye Dembélé⁴^,5^,6^,7 , Christelle Thibault⁴^,5^,6^,7 , Axel Defays¹^,2^,3 , Gilles Bessou¹^,2^,3 , Huichun Xu⁸ , Eric Vivier¹^,2^,3^,9 , MacLean Sellars⁴^,5^,6^,7 , Philippe Pierre¹^,2^,3 , Franck R Sharp⁸ , Susan Chan⁴^,5^,6^,7 , Philippe Kastner⁴^,5^,6^,7 and Marc Dalod¹^,2^,3

¹CIML (Centre d'Immunologie de Marseille-Luminy), Université de la Méditerranée, Parc scientifique de Luminy case 906, Marseille F-13288, France

²U631, INSERM (Institut National de la Santé et de la Recherche Médicale), Parc scientifique de Luminy case 906, Marseille F-13288, France

³UMR6102, CNRS (Centre National de la Recherche Scientifique), Parc scientifique de Luminy case 906, Marseille F-13288, France

⁴Hematopoiesis and leukemogenesis in the mouse, IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), rue Laurent Fries, ILLKIRCH F-67400, France

⁵U596, INSERM, rue Laurent Fries, ILLKIRCH F-67400, France

⁶UMR7104, CNRS, rue Laurent Fries, ILLKIRCH F-67400, France

⁷UM41, Université Louis Pasteur, rue Laurent Fries, Strasbourg F-67400, France

⁸The Medical Investigation of Neurodevelopmental Disorders Institute, University of California at Davis Medical Center, Sacramento, CA 95817, USA

⁹Hôpital de la Conception, Assistance Publique-Hôpitaux de Marseille, Boulevard Baille, Marseille F-13385, France

¹⁰Current address: Genomics Institute of the Novartis Research Foundation, John Jay Hopkins Drive, San Diego, CA 92121, USA

author email corresponding author email

Genome Biology 2008, 9:R17doi:10.1186/gb-2008-9-1-r17


Published:	24 January 2008

Subject areas: Immunology, Evolution

Additional files

Additional file 1:

Raw data for the mouse gene chip compendium.

Format: XLS Size: 2.5MB Download file

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Additional file 2:

Raw data for the human gene chip compendium.

Format: XLS Size: 6.1MB Download file

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Additional file 3:

Raw data for the human/mouse gene chip compendium.

Format: XLS Size: 2.8MB Download file

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Additional file 4:

Raw data for the IKDC gene chip compendium.

Format: XLS Size: 1MB Download file

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Additional file 5:

Mouse DC subset gene signatures according to our datasets with confirmation from two other independent datasets (one for pDCs and one for cDC subsets).

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Additional file 6:

Results of PCA for investigation of the relationships between in vitro derived GM-CSF DCs and LN-DCs in mouse and human.

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Additional file 7:

Real-time PCR data for the pattern of expression of 27 genes across mouse leukocyte subsets.

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Additional file 8:

PACSIN1 expression in human pDCs versus PBMCs by RT-PCR and western blotting.

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