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Specific transcriptomic signatures identified in the leukocyte populations studied |
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| Expression ratio (log2) of specific genes* |
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|
|
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| Cell type |
3-4 |
2-3 |
1-2 |
0,4-1 |
|
|
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| Myeloid cells |
- |
Steap4; Clec4d; Clec4e; Fpr1 |
Nfe2; Mpp1; Snca; Ccr1; Slc40a1; S100a9; Cd14; Tlr4; F5; Fcgr3; Fpr-rs2; Tlr2; Abhd5; Gca; Atp6v1b2; Ier3; Sod2; Pilra; Slc11a1 |
Sepx1; Ninj1; Hp; Sdcbp; Bst1; Ifit1; S100a8; Adipor1; Bach1; Marcks; Pira2; Wdfy3; Ifrd1; Fcho2; Csf3r; C5ar1; Cd93; Snap23; Cebpb; Clec7a; Yipf4; Hmgcr; Slc31a2; Fbxl5 |
| Pan-DC |
Flt3 |
Sh3tc1 |
Trit1; Bri3bp; Prkra; Etv6; Tmed3; Bahcc1; Scarb1 |
|
| cDC |
- |
- |
Arhgap22; Btbd4; Slamf8; 9130211I03Rik; Nav1 |
C2ta; Avpi1; Spint1; Cs |
| pDC |
Epha2; Pacsin1; Zfp521; Sh3bgr |
Tex2; Runx2; Atp13a2; Maged1; Tm7sf2; Tcf4; Gpm6b; Cybasc3 |
Nucb2; Alg2; Pcyox1; LOC637870; Scarb2; Dnajc7; Trp53i13; Plac8; Pls3; Tlr7; Ptprs; Bcl11a |
|
| B cells |
Ebf1; Cd19; Klhl14 |
Bank1; Pax5 |
Blr1; Ralgps2; Cd79b; Pou2af1; Fcer2a; Cr2; Cd79a; Fcrla |
Ms4a1; Blk; Cd72; Syvn1; BC065085; Fcrl1; Phtf2; Tmed8; Grap; Pip5k3; Pou2f2 |
| NK cells |
- |
Ncr1 |
Tbx21; Osbpl5 |
Rgs3; 1700025G04Rik; Plekhf1; Fasl; Zfpm1; Edg8; Cd160; Klrd1; Il2rb; Il18rap; Ctsw; Ifng; Prf1; Sh2d2a; Llgl2; Gpr178; Prkx; Gab3; Nkg7; Cst7; Sntb2; Runx3; Myo6; F2r; Vps37b; Dnajc1; Gfi1 |
| Pan-T cells |
- |
Camk4; E430004N04Rik; Trat1 |
Cxcr6; Tnfrsf25; Ccdc64; Plcg1 |
Cd3e; Cd5; Lrig1; Cd3g; Ubash3a; Cd6; Lat; Bcl11b; Tcf7; Icos |
| CD8 T cells |
- |
- |
- |
Gzmk |
| CD4 T cells |
- |
Ctla4 |
- |
Icos; Tnfrsf25; Cd5; Cd28; Trat1 |
| Lymphocytes |
- |
- |
Ablim1; Lax1; D230007K08Rik; Rasgrp1; Bcl2 |
Spnb2; Cdc25b; Ets1; Sh2d2a; Ppp3cc; Cnot6l |
| Myeloid, B, DC |
- |
H2-DMb2; H2-DMb1 |
C2ta; March1; Aldh2; Bcl11a; Btk |
Ctsh; H2-Eb1; Cd74; Ctsz; Clic4; Kynu; 5031439G07Rik; Nfkbie; Unc93b1 |
| Non-DC |
Gimap4 |
- |
Vps37b |
Lck; Pde3b |
|
*Ratio expressed as Minimum expression among the cell types selected/Maximum expression among all other cell types. Genes already known to be preferentially expressed in the cell types selected are shown in boldface. | ||||
Robbins et al. Genome Biology 2008 9:R17 doi:10.1186/gb-2008-9-1-r17 |
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