Table 9

Expression of APC, DC and myeloid signature genes in CD16 cells

Dendritic cells

Myeloid cells

Ratio to DC




Probe set ID

Gene

BDCA1

BDCA3

pDC

Mono

Neu

CD16 cells

CD16

Mono

Neu


APC signature genes

203932_at

HLA-DMB

8,636*

7,929

5,894

5,194

173

2,581

0.3

0.6

<0.1

205101_at

CIITA

2,803

2,354

724

531

50

226

<0.1

0.2

<0.1

219574_at

MARCH1

587

777

544

1,214

58

810

1

2

<0.1

201425_at

ALDH2

9,279

7,841

6,034

8,504

706

1,760

0.2

0.9

<0.1

222891_s_at

BCL11A

569

747

4,502

310

50

213

<0.1

<0.1

<0.1

205504_at

BTK

1,120

822

1,132

1,409

281

1,786

2

1

0.3

202295_s_at

CTSH

6,197

2,528

1,211

3,949

75

2,440

0.39

0.6

<0.1

213831_at

DQA1

11,535

7,503

5,919

4,701

50

252

<0.1

0.4

<0.1

215536_at

DQB2

432

391

157

180

81

52

0.1

0.4

0.2

209312_x_at

DRB1

14,608

14,477

13,250

11,915

228

14,007

1

0.8

<0.1

209619_at

CD74

12,533

12,210

10,498

9,020

867

7,383

0.6

0.7

<0.1

210042_s_at

CTSZ

906

848

692

370

153

673

0.7

0.4

0.2

201560_at

CLIC4

920

305

663

3,023

165

354

0.4

3

0.2

217388_s_at

KYNU

2,414

1,059

2,204

3,516

50

3,738

2

1

<0.1

203927_at

NFKBIE

529

272

232

197

63

290

0.5

0.4

0.1

220998_s_at

UNC93B1

966

850

1,938

862

449

1,235

0.6

0.4

0.2

Pan-DC signature genes

206674_at

FLT3

3,032

5,883

2,169

208

<50

<50

<0.1

<0.1

<0.1

219256_s_at

SH3TC1

1,263

899

1,128

392

166

858

0.7

0.3

0.1

218617_at

TRIT1

1,159

1,246

1,851

509

<50

339

0.2

0.3

<0.1

231810_at

BRI3BP

691

735

836

298

146

279

0.3

0.4

0.2

209139_s_at

PRKRA

846

1,067

1,440

316

74

497

0.3

0.2

<0.1

225764_at

ETV6

2,172

2,432

1,726

1,143

938

941

0.4

0.5

0.4

208837_at

TMED3

1,317

1,852

1,859

665

<50

1,022

0.6

0.4

<0.1

219218_at

BAHCC1

87

86

250

<50

<50

<50

0.2

0.2

0.2

1552256_a_at

SCARB1

325

425

942

165

128

59

<0.1

0.2

0.1

Non-DC signature genes

219243_at

GIMAP4

68

<50

<50

4,404

3,504

1,334

20

65

52

221704_s_at

VPS37B

54

<50

<50

593

962

487

9

11

18

204891_s_at

LCK

<50

<50

<50

92

181

65

-

-

-

214582_at

PDE3B

78

<50

<50

129

625

114

1

2

8

Myeloid signature genes

225987_at

STEAP4

<50

<50

<50

877

6,090

<50

-

-

-

1552773_at

CLEC4D

<50

<50

<50

452

520

<50

-

-

-

222934_s_at

CLEC4E

214

124

133

2,837

5,885

229

1

13

28

202974_at

MPP1

591

281

377

3,721

2,408

1,341

2

6

4

205098_at

CCR1

93

<50

115

3,712

3,627

106

1

32

31

223044_at

SLC40A1

769

276

321

5,018

3,444

<50

-

6

4

224341_x_at

TLR4

94

<50

<50

1,411

2,869

540

6

15

31

204714_s_at

F5

<50

<50

<50

1,392

2,313

<50

-

-

-

203561_at

FCGR2A

1,010

44

51

2,985

7,151

2,857

3

3

7

210772_at

FPRL1

<50

<50

<50

389

3,454

70

3

-

-

204924_at

TLR2

904

211

57

2,870

5,548

1,606

2

3

6

215223_s_at

SOD2

1,474

946

528

3,528

7,599

4,236

3

2

5

222218_s_at

PILRA

1,168

150

136

2,899

4,035

3,982

3

2

3

210423_s_at

SLC11A1

81

60

38

1,767

2,930

3,334

41

22

36

203045_at

NINJ1

357

66

71

1,104

3,129

1,934

5

3

9

201669_s_at

MARCKS

521

389

<50

2,449

3,224

1,730

3

5

6

207697_x_at

LILRB2

1,271

78

774

3,353

3,711

4,903

4

3

3

1553297_a_at

CSF3R

1,902

409

156

3,433

6,687

282

0.2

2

4

220088_at

C5AR1

56

34

93

2,316

5,099

3,824

41

25

55

221698_s_at

CLEC7A

3,229

4,295

79

6,642

7,061

5,680

1

2

2

204204_at

SLC31A2

442

187

<50

1,579

2,047

1,671

4

4

5


*Average expression across replicates. Mono, monocyte; neu, neutrophil.

Robbins et al. Genome Biology 2008 9:R17   doi:10.1186/gb-2008-9-1-r17

Open Data