Figure 3.

Inferred history of ACE1 and ACE1-like clusters in filamentous fungi. The gray rectangle corresponds to the ancient core cluster of three genes (ACE1, RAP1, ORF3) that is common to all ACE1 clusters (pink) and ACE1-like clusters (orange). The black arrow denotes the inferred HGT of part B of the cluster from a donor related to M. grisea to the A. clavatus recipient. Dashed branches and smaller fonts indicate euascomycetes that were included in our analysis but lack the clusters entirely. Phylogenetic relationships are based on [27] and N Fedorova and N Khaldi, unpublished data, for the topology within the genus Aspergillus. The tree is not drawn to scale.