Table 2 |
||||
|
Selected transcripts |
||||
|
Total (fold change) |
p-value |
Polysome (fold change) |
p-value |
|
|
|
||||
|
Contribution from translation |
||||
|
SMARCA2 |
+ 1.46 |
NS |
+ 4.26 |
0.009 |
|
SMARCB1 |
- 4.00 |
NS |
+ 4.36 |
0.024 |
|
MEF2C |
+ 1.31 |
NS |
+ 3.98 |
0.004 |
|
MEF2D |
- 1.29 |
NS |
+ 2.35 |
0.018 |
|
NF-KBIA |
+ 1.24 |
NS |
+ 2.81 |
0.027 |
|
Oncostatin M receptor/IL6ST |
+ 1.24 |
NS |
+ 80.12 |
0.010 |
|
Caspase 8 |
- 1.92 |
NS |
+ 4.17 |
0.010 |
|
Caspase 9 |
+ 1.26 |
NS |
+ 3.50 |
0.025 |
|
OAS1 |
- 1.69 |
NS |
+ 4.82 |
0.016 |
|
IRF3 |
+ 1.00 |
NS |
+ 5.65 |
0.034 |
|
IFI16 |
+ 1.90 |
NS |
+ 54.11 |
0.009 |
|
RARA |
- 1.19 |
NS |
+ 2.69 |
0.050 |
|
RXRA |
+ 1.45 |
NS |
+ 2.17 |
0.004 |
|
RXRB |
- 1.23 |
NS |
+ 4.45 |
0.013 |
|
STAT6 |
+ 1.29 |
NS |
+ 2.99 |
0.011 |
|
EGR1 |
+ 1.52 |
NS |
+ 12.34 |
0.050 |
|
IGFBP1 |
+ 1.87 |
NS |
+ 7.38 |
0.010 |
|
MMP3 |
- 1.10 |
0.044 |
+ 6.87 |
0.047 |
|
SLC27A3 |
+ 2.03 |
0.043 |
+ 22.77 |
0.031 |
|
Contribution from transcription |
||||
|
PPARA |
+ 2.25 |
0.002 |
+ 2.49 |
0.026 |
|
PPARD |
+ 2.00 |
0.001 |
+ 3.80 |
0.005 |
|
CEBPA |
+ 3.91 |
0.050 |
+ 3.86 |
0.004 |
|
HLF |
+ 14.11 |
0.001 |
+ 17.09 |
0.015 |
|
ADH1B |
+ 354.89 |
0.021 |
+ 335.41 |
0.050 |
|
ADH1C |
+ 38.86 |
0.050 |
+ 27.37 |
0.003 |
|
ADH6 |
+ 18.22 |
0.029 |
+ 46.55 |
0.050 |
|
ApoH |
+ 6.49 |
0.050 |
+ 7.59 |
0.008 |
|
SERPINA1 |
+ 2.70 |
0.007 |
+ 10.69 |
0.015 |
|
SERPINA4 |
+ 4.86 |
0.050 |
+ 18.58 |
0.037 |
|
SERPINF2 |
+ 9.82 |
0.050 |
+ 2.30 |
0.000 |
|
Complement component 1, s |
+ 2.30 |
0.008 |
+ 3.40 |
0.041 |
|
Complement component 3 |
+ 2.28 |
0.050 |
+ 2.98 |
0.042 |
|
Complement component 4A |
+ 6.65 |
0.006 |
+ 7.86 |
0.025 |
|
Complement component 5 |
+ 3.42 |
0.039 |
+ 2.33 |
0.014 |
|
Complement component 6 |
+ 36.20 |
0.000 |
+ 48.42 |
0.043 |
|
Fibrinogen A |
+ 15.35 |
0.017 |
+ 9.84 |
0.022 |
|
Fibrinogen B |
+ 17.13 |
0.033 |
+ 15.02 |
0.033 |
|
Fibrinogen G |
+ 14.79 |
0.015 |
+ 11.55 |
0.016 |
|
TNFSF10/TRAIL |
+ 7.08 |
0.002 |
+ 5.15 |
0.007 |
|
IL6R |
+ 9.30 |
0.000 |
+ 15.95 |
0.012 |
|
BMP2 |
- 2.08 |
0.000 |
- 2.00 |
0.014 |
|
PDGFB |
- 2.53 |
0.013 |
- 2.62 |
0.003 |
|
Translational repression |
||||
|
MME |
+ 18.16 |
0.025 |
+ 1.48 |
NS |
|
E-cadherin |
+ 8.64 |
0.043 |
- 1.35 |
NS |
|
CYP3A4 |
+ 357.26 |
NS |
+ 11.29 |
0.015 |
|
CYP3A5 |
+ 20.14 |
0.012 |
+ 4.66 |
NS |
|
CYP2B6 |
+ 22.78 |
0.021 |
+ 2.55 |
0.016 |
|
CYP7B1 |
+ 2.85 |
0.048 |
- 1.49 |
NS |
|
CYP2A6 |
+ 2.85 |
0.002 |
- 1.51 |
NS |
|
CYP2C19 |
+ 17.70 |
NS |
+ 1.35 |
0.032 |
|
CYP4F3 |
+ 19.58 |
0.038 |
+ 5.14 |
NS |
|
TGFBR2 |
+ 6.78 |
0.001 |
+ 1.15 |
NS |
|
VEGF |
+ 4.67 |
0.034 |
- 2.70 |
NS |
|
Insulin receptor |
+ 3.83 |
<0.001 |
+ 1.20 |
NS |
|
Leptin receptor |
+ 3.07 |
0.007 |
+ 1.34 |
NS |
|
|
||||
|
NS, not significant. |
||||
|
Parent and Beretta Genome Biology 2008 9:R19 doi:10.1186/gb-2008-9-1-r19 |
||||
