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Protein interactions in human genetic diseases

Benjamin Schuster-Böckler* and Alex Bateman

Genome Biology 2008, 9:R9 doi:10.1186/gb-2008-9-1-r9

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The apoptotic machinery as a biological complex system: analysis of its omics and evolution, identification of candidate genes for fourteen major types of cancer, and experimental validation in CML and neuroblastoma

Cinzia Di Pietro, Marco Ragusa, Davide Barbagallo, Laura R Duro, Maria R Guglielmino, Alessandra Majorana, Rosario Angelica, Marina Scalia, Luisa Statello, Loredana Salito, Luisa Tomasello, Salvo Pernagallo, Salvo Valenti, Vito D'Agostino, Patrizio Triberio, Igor Tandurella, Giuseppe A Palumbo, Piera La Cava, Viviana Cafiso, Taschia Bertuccio, Maria Santagati, Giovanni Li Destri, Salvatore Lanzafame, Francesco Di Raimondo, Stefania Stefani, Bud Mishra, Michele Purrello BMC Medical Genomics 2009, 2:20 (30 April 2009)

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Systems medicine: the future of medical genomics and healthcare

Charles Auffray, Zhu Chen, Leroy Hood Genome Med 2009, 1:2 (20 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Editor’s summary

Systems approaches to medicine will transform the way drugs are developed and will enable medicine to become predictive, personalized, preventive and participatory.

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