Protein interactions in human genetic diseases

Benjamin Schuster-Böckler and Alex Bateman

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK

author email corresponding author email

Genome Biology 2008, 9:R9doi:10.1186/gb-2008-9-1-r9


Published:	16 January 2008

Subject areas: Bioinformatics, Biochemistry and structural biology, Genetics

Additional files

Additional data file 1:

All 1,428 predicted interacting mutations and the corresponding structural templates, homologous interactions and surface accessibilities.

Format: XLS Size: 386KB Download file

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Additional data file 2:

119 disease mutations linked to protein interaction defects, derived from the scientific literature.

Format: XLS Size: 72KB Download file

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Additional data file 3:

Error bars for the predicted set were calculated by randomly resampling 1,428 residues from all mutations 1,000 times and calculating the standard deviation.

Format: PDF Size: 18KB Download file

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