Genome Biology

official impact factor 6.89

Open Access Highly Access Method

Protein interactions in human genetic diseases

Benjamin Schuster-Böckler* and Alex Bateman

Author Affiliations

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK

For all author emails, please log on.

Genome Biology 2008, 9:R9 doi:10.1186/gb-2008-9-1-r9

Published: 16 January 2008

Additional files

Additional data file 1:

All 1,428 predicted interacting mutations and the corresponding structural templates, homologous interactions and surface accessibilities.

Format: XLS Size: 386KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 2:

119 disease mutations linked to protein interaction defects, derived from the scientific literature.

Format: XLS Size: 72KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 3:

Error bars for the predicted set were calculated by randomly resampling 1,428 residues from all mutations 1,000 times and calculating the standard deviation.

Format: PDF Size: 18KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data