ResearchDistinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas1 Department of Tumor Genetics, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg, 69120, Germany 2 Department of Biostatistics, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg, 69120, Germany 3 Theoretical Bioinformatics, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg, 69120, Germany 4 Department of Pediatric Oncology, University Children's Hospital of Cologne, Kerpener Strasse 62, Cologne, 50924, Germany 5 Division of Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, Heidelberg, 69120, Germany 6 Center for Medical Genetics, Ghent University Hospital, De Pintelaan 185, Ghent, 9000, Belgium
Genome Biology 2008, 9:R150doi:10.1186/gb-2008-9-10-r150
Subject areas: Cancer, Genome studies, Molecular biology Additional filesAdditional data file 1: Cluster map of genetic programs regulated by conditional expression of c-MYC and MYCN proteins in SH-EPMYCN cells. Format: PDF Size: 1.1MB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 2: Detailed methods and materials. Format: DOC Size: 62KB Download file This file can be viewed with: Microsoft Word Viewer Additional data file 3: ChIP-chip results of MYCN/c-MYC target genes in the Kelly cell line. Format: PDF Size: 722KB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 4: ChIP-chip results of MYCN/c-MYC target genes in the SJ-NB12 cell line. Format: PDF Size: 687KB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 5: MYCN/c-MYC target genes, which grouped in class 1 and 2. Format: XLS Size: 27KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 6: MYCN/c-MYC target genes, which grouped in class 4. Format: XLS Size: 36KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 7: MYCN/c-MYC target genes, which grouped in class 3. Format: XLS Size: 34KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 8: Genes and primers selected to confirm ChIP-chip results. Format: XLS Size: 37KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 9: Association of MYCN/c-MYC induced genes with stage 4s-NA neuroblastomas using the Global test. Format: PDF Size: 1.1MB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 10: Association of MYCN/c-MYC induced genes with stage 4-NA neuroblastomas using the Global test. Format: PDF Size: 1.2MB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 11: Association of MYCN/c-MYC induced genes with MYCN amplified neuroblastomas using the Global test. Format: PDF Size: 1.4MB Download file This file can be viewed with: Adobe Acrobat Reader Additional data file 12: Patient data. Format: XLS Size: 95KB Download file This file can be viewed with: Microsoft Excel Viewer |


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