Table 2

Expression trends of proteins categorized under Gene Ontology terms

Organ

GO ID number

GO term

Proteins considered

t-Test of slope between day 1 and day 5

Slope


H

GO:0004857

Enzyme inhibitor activity

6

1.9E-02

-0.19

T

GO:0004857

Enzyme inhibitor activity

6

0.007

-0.41

T

GO:0004386

Helicase activity

4

0.016

-0.37

T

GO:0016787

Hydrolase activity

80

0.002

-0.10

H

GO:0003676

Nucleic acid binding

18

7.2E-05

-0.24

T

GO:0003676

Nucleic acid binding

38

7.8E-09

-0.33

H

GO:0000166

Nucleotide binding

36

4.8E-03

-0.09

T

GO:0000166

Nucleotide binding

72

0.022

-0.08

H

GO:0016491

Oxidoreductase activity

19

1.8E-02

0.18

H

GO:0004871

Signal transducer activity

3

4.7E-02

-0.22

H

GO:0003735

Structural constituent of ribosome

18

1.5E-08

-0.41

T

GO:0003735

Structural constituent of ribosome

35

8.4E-16

-0.34

T

GO:0022892

Substrate-specific transporter activity

34

0.035

0.11

T

GO:0008135

Translation factor activity, nucleic acid binding

10

0.037

-0.24

H

GO:0022857

Transmembrane transporter activity

4

3.9E-02

-0.11

T

GO:0022857

Transmembrane transporter activity

27

0.010

0.12


Proteins were categorized under third-level molecular function terms and were evaluated as a group to assess whether their expression trends were age-regulated by performing paired t-tests comparing values from day 1 and day 5 of larval development, reporting the average slope between these two days if p < 0.05 in either the solid tissue (T) or hemolymph (H). The total number of proteins belonging under a particular GO term considered in the calculation is listed under 'Proteins considered'.

Chan and Foster Genome Biology 2008 9:R156   doi:10.1186/gb-2008-9-10-r156

Open Data