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Correspondence

Do we use the appropriate controls for the identification of informative methylation markers for early cancer detection?

Yasser Riazalhosseini* and Jörg D Hoheisel

Author Affiliations

Functional Genome Analysis, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany

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Genome Biology 2008, 9:405  doi:10.1186/gb-2008-9-11-405

Published: 26 November 2008

Abstract

It is possible to miss potential DNA methylation markers of tumorigenesis because of the initial filtering of profiling results on the basis of inappropriate controls.