Figure 2.

Alignment of LOLA isoforms. The alignment of the carboxy-terminal C₂H₂ DNA-binding zinc finger domains of the seven detected LOLA isoforms (CG12052). Six isoforms have two C₂H₂ zinc-finger domains, isoform PP has a C₂H₂ DNA-binding zinc-finger domain and a C₂HC zinc finger domain. Zinc-binding residues (cysteines and histidines) are marked in red, and structurally important residues marked in green. The symbols below the alignment indicate the degree of conservation of the aligned residues: asterisk, completely conserved column; colon, highly conserved column; single dot, some conservation.