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Cell death upon epigenetic genome methylation: a novel function of methyl-specific deoxyribonucleases

Eri Fukuda12, Katarzyna H Kaminska34, Janusz M Bujnicki134 and Ichizo Kobayashi125*

Author Affiliations

1 Laboratory of Social Genome Sciences, Department of Medical Genome Sciences, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan

2 Graduate Program in Biophysics and Biochemistry, Graduate School of Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan

3 International Institute of Molecular and Cell Biology, Trodena 4, 02-109 Warsaw, Poland

4 Faculty of Biology, Adam Mickiewicz University, Umultowska 89, 61-614 Poznan, Poland

5 Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan

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Genome Biology 2008, 9:R163  doi:10.1186/gb-2008-9-11-r163

Published: 21 November 2008

Additional files

Additional data file 1:

Genomic contexts of mcrB homologs.

Format: DOC Size: 334KB Download file

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Open Data

Additional data file 2:

Phylogenetic trees of McrB and McrC.

Format: PDF Size: 2MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional data file 3:

Neighbors of mcrB homologs.

Format: DOC Size: 39KB Download file

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Open Data

Additional data file 4:

Phylogenetic tree of the 16S rRNA gene.

Format: PDF Size: 1.4MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data