Figure 1.

Diversity at assayed SNPs (SNP π). (a) Nonsynonymous and silent SNP diversity by population. Significantly lower nonsynonymous SNP diversity (determined by bootstrapping) is indicated by asterisks: *P < 0.05; **P < 0.001; ***P < 0.0001. Error bars indicate 95% confidence intervals derived from bootstrapping. (b) SNP π on chromosome 7 for chloroquine resistant (red) and chloroquine sensitive (blue) samples. The disparity in diversity near 460 kb indicated with gray shading likely corresponds to a selective sweep associated with the pfcrt locus.