Genome Biology

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Open Access Research

Evolutionary-new centromeres preferentially emerge within gene deserts

Mariana Lomiento1, Zhaoshi Jiang2, Pietro D'Addabbo1, Evan E Eichler3,2 and Mariano Rocchi1*

Author Affiliations

1 Department of Genetics and Microbiology, University of Bari, Via Amendola 165/A, Bari 70126, Italy

2 Department of Genome Sciences, University of Washington School of Medicine Seattle, 1705 NE Pacific St, Seattle, WA 98195, USA

3 Howard Hughes Medical Institute, 1705 NE Pacific St, Seattle, WA 98195, USA

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Genome Biology 2008, 9:R173 doi:10.1186/gb-2008-9-12-r173

Published: 16 December 2008

Additional files

Additional data file 1:

Evolutionary history of chromosome 8 in primates.

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Open Data

Additional data file 2:

Examples of FISH experiments.

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Additional data file 3:

Human probes used to track the evolutionary history of chromosome 8.

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Additional data file 4:

Species-specific BAC clones used in FISH experiments to detect pericentromeric segmental duplications.

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Open Data