Research
Selective maintenance of Drosophila tandemly arranged duplicated genes during evolution
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* Corresponding authors: David Torrents david.torrents@bsc.es - Miguel Manzanares mmanzanares@cnic.es
1 Instituto de Investigaciones Biomédicas CSIC-UAM, Arturo Duperier 4, 28029 Madrid, Spain
2 Barcelona Supercomputing Center, Jordi Girona 31, 08034 Barcelona, Spain
3 Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D-01307 Dresden, Germany
4 European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
5 ICREA and Institute for Research in Biomedicine (IRB), Parc CientÃfic de Barcelona, Josep Samitier 1-5, 08028 Barcelona, Spain
6 ICREA and Barcelona Supercomputing Center, Jordi Girona 31, 08034 Barcelona, Spain
7 Centro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernandez Almagro 3, 28029 Madrid, Spain
8 Current address: Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto 606-8501 Japan
Genome Biology 2008, 9:R176 doi:10.1186/gb-2008-9-12-r176
Published: 16 December 2008Additional files
Additional data file 1:
Distribution of paralogous gene group size and distance.
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Additional data file 2:
Statistical test used to define tandemly and dispersed duplicated genes.
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Additional data file 3:
Over- and underrepresented GO categories in TDGs subdivided by dS ranges, compared to dispersed duplicates.
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Additional data file 4:
Over- and underrepresented GO categories in TDGs compared to dispersed duplicates.
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Additional data file 5:
Over- and underrepresented GO categories in conserved TDGs compared to dispersed duplicates.
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Additional data file 6:
Number of D. melanogaster genes included in each category of selected GO terms and gene sets.
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Additional data file 7:
Evolutionarily conserved TDGs are enriched in 'complex' genes.
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Additional data file 8:
Groups of TDGs conserved between D. melanogaster and A. gambiae used in the embryonic co-expression analysis.
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Additional data file 9:
Groups of genes in conserved linkage between D. melanogaster and A. gambiae that are not tandem duplicates used in the embryonic co-expression analysis.
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Additional data file 10:
Stringency in the definition of conserved TDGs as used in this study.
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Additional data file 11:
Conserved TDGs that are co-expressed in the Drosophila embryo that have been previously described in the literature.
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Additional data file 12:
D. melanogaster gene sets used in this study.
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