Quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites
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* Corresponding author: Zbynek Bozdech zbozdech@ntu.edu.sg
Genome Biology 2008, 9:R177 doi:10.1186/gb-2008-9-12-r177
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Paul M Southworth, John E Hyde, Paul FG Sims Malaria Journal 2011, 10:315 (25 October 2011) Elegant methodology enabling the absolute quantification of pre-selected plasmodial proteins using a combined QconCAT SRM-MS approach. The novel method would clearly offer a direct route to quantifying potentially any protein in this most difficult of proteomes.
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Reality check for malaria proteomics Robert E Sinden Genome Biology 2009, 10:211 (26 February 2009) Post-translationally modified protein isoforms are common in red blood cell stages of the malaria parasite. |