Genome Biology

official impact factor 6.89

Open Access Highly Access Research

Quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites

Bernardo J Foth, Neng Zhang, Sachel Mok, Peter R Preiser and Zbynek Bozdech*

Author Affiliations

School of Biological Sciences, Nanyang Technological University, Nanyang Drive, 637551 Singapore

For all author emails, please log on.

Genome Biology 2008, 9:R177 doi:10.1186/gb-2008-9-12-r177

Published: 17 December 2008

Additional files

Additional data file 1:

Quantitative 2D-DIGE raw data. The panels show the individual raw data points for all protein isoforms identified in this study. The volume ratios have not been mean-centered around zero.

Format: PDF Size: 1.2MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional data file 2:

Expression profiles comparing relative mRNA and protein abundance. See legend to Figure 5 in the main text.

Format: PDF Size: 1.1MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional data file 3:

Microarray data for the 24 genes corresponding to the parasite proteins identified in this study. The transcript measurements represent normalized ratios of the timepoint samples versus a P. falciparum RNA pool and have been log2-transformed, averaged (in the case of multiple oligos per gene), and mean-centered around zero.

Format: XLS Size: 20KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 4:

Complete microarray raw data. The transcript measurements represent normalized ratios of the timepoint samples versus a P. falciparum RNA pool and have been log2 transformed. These microarray data are also available at the Gene Expression Omnibus data base at the National Center for Biotechnology Information [GEO:GSE13251].

Format: XLS Size: 1.5MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data