Table 3 |
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|
Embryo dissections to determine time of death of homozygotes |
||||||
| 10.5 dpc |
14.5 dpc |
17.5/18.5 dpc |
||||
|
|
|
|
||||
| Name |
Normal |
Abnormal or resorbed |
Normal |
Abnormal or resorbed |
Normal |
Abnormal or resorbed |
|
|
||||||
| MommeD3 |
48 (60%) |
32 (40%)* |
||||
| MommeD3 (F1) |
80 (74%) |
28 (26%)* † |
||||
| MommeD5 |
35 (74%) |
12 (26%)* ‡ |
42 (72%) |
16 (28%)* |
||
| MommeD6 |
38 (63%) |
22 (37%)* |
25 (62.5%) |
15 (37.5%)* |
||
| MommeD7 |
44 (85%) |
8 (15%)§ |
63 (74%) |
22 (26%) |
||
| MommeD8 |
101 (94%) |
7 (6%) |
||||
| MommeD9 |
16 (64%) |
9 (36%)* |
19 (59%) |
13 (41%)* |
||
| MommeD10 |
54 (93%) |
4 (7%) |
86 (88%)¶ |
12 (12%)¥ |
||
| Control cross |
34 (94%) |
2 (6%) |
266 (93%) |
19 (7%) |
||
|
|
||||||
|
†The abnormal embryos from which DNA could be extracted (17) were genotyped across the linked interval and all shown to be MommeD3-/-. ‡These abnormal (very small) embryos were genotyped and shown to be MommeD5-/-. ¶These normal embryos were genotyped and found to have the expected ratio of MommeD10+/+, MommeD10-/+ and MommeD10-/- embryos. ¥Four of the abnormal embryos were able to be genotyped: two were MommeD10-/+ and two were MommeD10-/-. *p < 0.0001; §p < 0.05. |
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|
Ashe et al. Genome Biology 2008 9:R182 doi:10.1186/gb-2008-9-12-r182 |
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