Bias correction improves concordance of replicates in a glioma gene expression study. Hierarchical clustering was performed as in Figure 1. (a) The unfiltered, uncorrected data results in neither of the two replicate pairs together. (b) Bias correction as described in this paper results in one of two replicate pairs clustered together.
Eklund and Szallasi Genome Biology 2008 9:R26 doi:10.1186/gb-2008-9-2-r26