Finding exonic islands in a sea of non-coding sequence: splicing related constraints on protein composition and evolution are common in intron-rich genomesDepartment of Biology and Biochemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK
Genome Biology 2008, 9:R29doi:10.1186/gb-2008-9-2-r29
Subject areas: Evolution, Molecular biology, Bioinformatics Additional filesAdditional data file 1: Amino acid trends for all species and associated statistics. Format: XLS Size: 130KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 2: Amino acid trends and associated statistics for homology-reduced gene sets of D. melanogaster and C. elegans. Format: XLS Size: 50KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 3: Protocol for homology reduction of C. elegans and D. melanogaster orthologues. Format: DOC Size: 24KB Download file This file can be viewed with: Microsoft Word Viewer Additional data file 4: Protocol for covariate analysis of abundance trends. Format: DOC Size: 43KB Download file This file can be viewed with: Microsoft Word Viewer Additional data file 5: Covariates of amino acid trends by species. Format: XLS Size: 16KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 6: By-species cross-correlations for covariates of amino acid trends. Format: XLS Size: 33KB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 7: Best blast hits of SR proteins against C. neoformans genes and Pfam domain scores in those genes. Format: TXT Size: 6KB Download file Additional data file 8: Analysis of ESE positioning in relation to the reading frame. Format: DOC Size: 179KB Download file This file can be viewed with: Microsoft Word Viewer Additional data file 9: Re-sampling distributions of evolutionary rates. Format: DOC Size: 77KB Download file This file can be viewed with: Microsoft Word Viewer Additional data file 10: Rank correlations between KA and the proportion of sequence near the exon-intron boundary. Format: DOC Size: 32KB Download file This file can be viewed with: Microsoft Word Viewer Additional data file 11: Detailed characterization of specific local discontinuities. Format: DOC Size: 39KB Download file This file can be viewed with: Microsoft Word Viewer Additional data file 12: Sources of exon datasets. Format: DOC Size: 41KB Download file This file can be viewed with: Microsoft Word Viewer Additional data file 13: Gene model IDs from which exons were derived. Format: XLS Size: 5.8MB Download file This file can be viewed with: Microsoft Excel Viewer Additional data file 14: Examples of locally discontinuous preference trends. Format: DOC Size: 64KB Download file This file can be viewed with: Microsoft Word Viewer Additional data file 15: Local discontinuities across selected species. Format: DOC Size: 75KB Download file This file can be viewed with: Microsoft Word Viewer |


on Google Scholar







author email
corresponding author email