Table 3

Amino acids significantly preferred (-) or avoided (+) at 3' (top rows) and 5' (bottom rows) exon ends of C. neoformans compared to human

Amino acids*†



A
C
D
E
F
G
H
I
K
L4
L2
M
N
P
Q
R4
R2
S4
S2
T
V
W
Y
Species (number of exons)

+3

-7

-3


-2
-1

-5

-6
+2

+1
-4

+4




Human (178,438): 3'

-6

+1
-2
+4
-7
-1
+3
-3




+6
-5
+2

+5



-4
C. neoformans (28,446): 3'
























+2


-4
-5

+7
-3
-1

-2
-8
-6
+1
+4
+3
-7

+5
+6



Human (178438): 5'

-9


-5
-7

-3


-1
-6

+2

+3
-4
+1


-8
-10
-2
C. neoformans (28,446): 5'

*Indices signify rank order of slope coefficients, separately for negative and positive trends. L2, R2, S2 and L4, R4, S4 signify the two-fold and four-fold degenerate blocks of leucine, arginine, and serine, respectively.

Warnecke et al. Genome Biology 2008 9:R29   doi:10.1186/gb-2008-9-2-r29