Functional protein divergence in the evolution of Homo sapiens
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* Corresponding author: Nuria Lopez-Bigas nuria.lopez@upf.edu
Genome Biology 2008, 9:R33 doi:10.1186/gb-2008-9-2-r33
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Conservation and divergence of known apicomplexan transcriptional regulons Kobby Essien, Christian J Stoeckert BMC Genomics 2010, 11:147 (3 March 2010) Transcription factors have diverged considerably between Plasmodium falciparum and other species of Apicomplexan parasites, as only three-fifths of the transcriptional networks are broadly conserved, and the associations between transcription factors and their target genes have changed.
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The conservation and evolutionary modularity of metabolism José M PeregrÃn-Alvarez, Chris Sanford, John Parkinson Genome Biology 2009, 10:R63 (12 June 2009) A novel evolutionary analysis of metabolic networks across 26 taxa reveals a highly-conserved but flexible core of metabolic enzymes. |
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Co-evolutionary networks of genes and cellular processes across fungal species Tamir Tuller, Martin Kupiec, Eytan Ruppin Genome Biology 2009, 10:R48 (5 May 2009) Two new measures of evolution are used to study co-evolutionary networks of fungal genes and cellular processes; links between co-evolution and co-functionality are revealed. |
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Cinzia Di Pietro, Marco Ragusa, Davide Barbagallo, Laura R Duro, Maria R Guglielmino, Alessandra Majorana, Rosario Angelica, Marina Scalia, Luisa Statello, Loredana Salito, Luisa Tomasello, Salvo Pernagallo, Salvo Valenti, Vito D'Agostino, Patrizio Triberio, Igor Tandurella, Giuseppe A Palumbo, Piera La Cava, Viviana Cafiso, Taschia Bertuccio, Maria Santagati, Giovanni Li Destri, Salvatore Lanzafame, Francesco Di Raimondo, Stefania Stefani, Bud Mishra, Michele Purrello BMC Medical Genomics 2009, 2:20 (30 April 2009) |
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Conservation of core gene expression in vertebrate tissues Esther T Chan, Gerald T Quon, Gordon Chua, Tomas Babak, Miles Trochesset, Ralph A Zirngibl, Jane Aubin, Michael JH Ratcliffe, Andrew Wilde, Michael Brudno, Quaid D Morris, Timothy R Hughes Journal of Biology 2009, 8:33 (16 April 2009) High conservation of tissue-specific expression is found across vertebrates yet there is a lack of conservation in common regulatory sequences/signatures.
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Patterns of evolutionary constraints on genes in humans Subhajyoti De, Nuria Lopez-Bigas, Sarah A Teichmann BMC Evolutionary Biology 2008, 8:275 (7 October 2008) |