Research
Systems biology meets stress ecology: linking molecular and organismal stress responses in Daphnia magna
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* Corresponding author: Lars-Henrik Heckmann lhh@dmu.dk
1 University of Reading, School of Biological Sciences, Environmental Biology, Philip Lyle Building, Reading, RG6 6BX, UK
2 University of Aarhus, National Environmental Research Institute, Department of Terrestrial Ecology, Vejlsøvej, DK-8600, Silkeborg, Denmark
3 University of California, School of Veterinary Medicine, Department of Anatomy, Physiology and Cell Biology, Davis, California 95616, USA
4 AstraZeneca Global SHE, Brixham Environmental Laboratory, Devon, TQ5 8BA, UK
5 Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth, PL1 3DH, UK
6 Syngenta Crop Protection AG, 4002 Basel, Switzerland
Genome Biology 2008, 9:R40 doi:10.1186/gb-2008-9-2-r40
Published: 21 February 2008Additional files
Additional data file 1:
Presented is a table listing all the cDNAs (annotated) that responded to ibuprofen treatment on the D. magna microarray.
Format: PDF Size: 121KB Download file
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Additional data file 2:
Presented is a table showing the relative expression and GO of the unique D. magna genes responding to acute ibuprofen exposure.
Format: PDF Size: 109KB Download file
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Additional data file 3:
Presented is a table displaying QPCR confirmation of selected D. magna genes responding on the cDNA microarray.
Format: PDF Size: 81KB Download file
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Additional data file 4:
Presented is an image of a D. magna embryo arrested at developmental stage 1 to 2 after maternal exposure to ibuprofen.
Format: PDF Size: 216KB Download file
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Additional data file 5:
Presented is a document with supplementary methods on microarray hybridization and microarray construction.
Format: PDF Size: 55KB Download file
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Additional data file 6:
Presented are MA plots of raw and normalized microarray data
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Additional data file 7:
Presented is a table showing water chemical parameters measured during the follow-up experiments.
Format: PDF Size: 76KB Download file
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Additional data file 8:
Presented is a table listing technical data on QPCR (for instance, primers and amplification efficiency) from the follow-up experiment assessing temporal expression of key genes responding to ibuprofen.
Format: PDF Size: 54KB Download file
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