Figure 6.

Predicted structure and estimated concentrations for the BIRC5 (apoptosis inhibitor survivin) gene in the 'central point' (synthetic data). (a) Structure of the different transcripts of the BIRC5 gene and location of probes used in the simulation. (b) Representation of the real and predicted splicing structures for the BIRC5 gene given by the probes used. In the graphic representing the real splicing structure the probes that match perfectly with the transcripts are represented by a white box (100% matching) and no hybridization is shown by a black box (0% matching). Gray levels show intermediate matching values. We have assumed that junction probes which include one side of the junction hybridize partially (20%). (c) Estimated relative concentrations of the three isoforms of BIRC5 gene. In each of the three graphics simulated and estimated relative concentration of each isoform is represented.