Log on / register
BioMed Central home | Journals A-Z | Feedback | Support
.reviews
 |  |  |  |  | 


Minireview

On the nature of thumbs

Günter P Wagner email and Alexander O Vargas

Department of Ecology and Evolutionary Biology, Yale University, Prospect Street, New Haven, CT 06520-8106, USA.

author email corresponding author email

Genome Biology 2008, 9:213doi:10.1186/gb-2008-9-3-213

Published: 4 March 2008

Subject areas: Development, Genetics

Abstract

Asymmetric regulation of Hox gene expression pre-dates the appearance of tetrapod digits, and was co-opted in the development of 'thumbness'. This asymmetric expression correlates with independent morphological evolutionary variation of digit 1.


Published by
© 1999-2008 BioMed Central Ltd unless otherwise stated < info@genomebiology.com >   Terms and conditions