Research
Computational identification of obligatorily autocatalytic replicators embedded in metabolic networks
-
* Corresponding author: Balázs Papp pappb@brc.hu
1 Collegium Budapest, Institute for Advanced Study, Szentháromság utca 2, Budapest H-1014, Hungary
2 Department of Plant Taxonomy and Ecology, Institute of Biology, Eötvös University, Pázmány Péter sétány 1/C, Budapest H-1117, Hungary
3 Faculty of Life Sciences, The University of Manchester, Oxford Road, Manchester M13 9PT, UK
4 Parmenides Center for the Study of Thinking, Kardinal Faulhaber Strasse, Munich D-80333, Germany
5 Current address: Institute of Biochemistry, Biological Research Center, Szeged H-6701, Hungary
Genome Biology 2008, 9:R51 doi:10.1186/gb-2008-9-3-r51
Published: 10 March 2008Additional files
Additional data file 1:
The figures (S1-S9) show the autocatalytic production of the identified metabolites. The table (S2) lists the relevant statistics for each metabolic network analyzed.
Format: DOC Size: 327KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional data file 2:
If the network reconstruction used abbreviated names for the metabolites, then the abbreviations are also included for ease of comparisons with the reconstruction.
Format: XLS Size: 393KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional data file 3:
The separate worksheets lists are: 1, the metabolites involved in the metabolic reconstruction, with their abbreviations and identifier used in the MetaCyc database; 2, the reactions with reaction ID, pathway, EC number and references; 3, the metabolites that cannot be produced in the network (dead end metabolites); 4, the reactions that were left out from the metabolic network, and the reason for the exclusion; and 5, the references and notes for the worksheets.
Format: XLS Size: 275KB Download file
This file can be viewed with: Microsoft Excel Viewer