Table 2

The presence/absence of pathways involved in the biosyntheses of potentially autocatalytic cofactors


NAD+
CoA
THF

Escherichia coli
+
+
+
Heliobacter pylori
+*
+
+
Staphylococcus aureus
P
+
+
Saccharomyces cerevisiae
P
+
+
Lactococcus lactis
P
+
+
Streptomyces coelicolor
+
+
+
Mycobacterium tuberculosis
+
+
+
Methanosarcina barkeri
P
+
P
Geobacter sulfurreducens
+*
+
+
Synechocystis
+
+
+
Minimal metabolism
P
P
P

A plus sign (+) indicates the biosynthetic route is fully present in the network; 'P' indicates the biosynthetic route is partially present in the network; asterisks indicate the biosynthetic route is slightly different from the one found in Synecocystis sp.

Kun et al. Genome Biology 2008 9:R51   doi:10.1186/gb-2008-9-3-r51