|
Details of representative functionally important fragments of FL8 enumerated using GO level 3 |
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| PDB (group number)* |
GO MF (EC number) |
PROSITE pattern |
Molecular function |
Functionally important fragment(s) (start: sequence (propensity))† |
P-value |
|
|
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| 1df9A (1) |
0003724 (3.4.21.91) |
- |
Dengue virus NS3 protease |
132: PGTSGSPI (30) |
4.17e-5 |
| 133: GTSGSPII (40) |
5.95e-8 |
||||
| 156: TRSGAYVS (24) |
0.007 |
||||
| 1e7uA (2) |
0016773 (2.7.1.153) |
PS00915 |
Phosphatidyl-inositol 3- and 4-kinase signatures 1 and 2 |
857: TESLDLCL (48) |
0.02 |
| PS00916 |
861: DLCLLPYG (23) |
0.04 |
|||
| 872: TGDKIGMI (29) |
0.03 |
||||
| 1tgj (3/4) |
0005160 |
PS00250‡ |
Cytokines (repair of tissue) |
27: DLGWKWVH (305) |
0.04 |
|
*The chain identifier is given after the four letter PDB code, wherever present. †Amino acids in bold either directly or indirectly participate in the enzyme function. ‡PROSITE pattern: (33-48, VHEPKGYYANFCSGPC). | |||||
Manikandan et al. Genome Biology 2008 9:R52 doi:10.1186/gb-2008-9-3-r52 |
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