Research
Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status
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* Corresponding author: Zhong Chen chenz@nidcd.nih.gov
- † Equal contributors
1 Head and Neck Surgery Branch, NIDCD, National Institutes of Health, Bethesda, MD 20892, USA
2 Department of Bioengineering, Smith Walk; University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
3 Center for Bioinformatics, Guardian Drive; University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
4 NIH-Pfizer Clinical Research Training Program Award; University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
5 Department of Statistics, The Wharton School, Walnut Street; University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
6 Department of Genetics, School of Medicine, Curie Boulevard; University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Genome Biology 2008, 9:R53 doi:10.1186/gb-2008-9-3-r53
Published: 11 March 2008Additional files
Additional data file 1:
NF-κB target genes differentially expressed in UM-SCC cell lines.
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Additional data file 2:
Gene Ontology annotations for NF-κB target genes in wild-type p53-deficient, mutant p53 and wild-type plus mutant p53 subsets of UM-SCC cells.
Format: PDF Size: 98KB Download file
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Additional data file 3:
Network lists generated by IPA based on gene sets regulated by NF-κB subunits RELA/p65 and NFκB1/p50.
Format: PDF Size: 140KB Download file
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