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Highly AccessReview

Genetic determinants of phenotypic diversity in humans

Nazli G Rahim, Olivier Harismendy, Eric J Topol and Kelly A Frazer email

Scripps Genomic Medicine, The Scripps Research Institute, North Torrey Pines Road MEM 275, La Jolla, CA 92037, USA

author email corresponding author email

Genome Biology 2008, 9:215doi:10.1186/gb-2008-9-4-215

Published: 24 April 2008

Subject areas: Genetics, Genome studies, Medicine, Methods

Abstract

New technologies for rapidly assaying DNA sequences have revealed that the degree and nature of human genetic variation is far more complex then previously realized. These same technologies have also resulted in the identification of common genetic variants associated with more than 30 human diseases and traits.


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