Lifting the veil on the transcriptome

Kevin P Callahan¹ and J Scott Butler¹^,2

¹Departments of Biochemistry and Biophysics, University of Rochester Medical Center, Elmwood Avenue, Rochester, NY 14642, USA

²Microbiology and Immunology, University of Rochester Medical Center, Elmwood Avenue, Rochester, NY 14642, USA

author email corresponding author email

Genome Biology 2008, 9:218doi:10.1186/gb-2008-9-4-218


Published:	24 April 2008

Subject areas: Plant biology, Cell biology, Genetics, Molecular biology, Model organisms

Abstract

Inhibition of the cellular RNA surveillance system in Arabidopsis thaliana results in the accumulation of thousands of transcripts arising from annotated and unannotated regions of the genome. This normally hidden transcriptome is replete with noncoding RNAs with the potential to regulate wide-ranging physiological activities.