Genome Biology

official impact factor 6.89

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ModuleMiner - improved computational detection of cis-regulatory modules: are there different modes of gene regulation in embryonic development and adult tissues?

Peter Van Loo*, Stein Aerts, Bernard Thienpont, Bart De Moor, Yves Moreau and Peter Marynen

Genome Biology 2008, 9:R66 doi:10.1186/gb-2008-9-4-r66

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Method   Open Access Highly Accessed

Genome-wide analysis of chromatin features identifies histone modification sensitive and insensitive yeast transcription factors

Chao Cheng, Chong Shou, Kevin Y Yip, Mark B Gerstein Genome Biology 2011, 12:R111 (7 November 2011)

A method that uses both chromatin features and motif identification to predict transcription factor binding sites

Method   Open Access Highly Accessed

Genome-wide prediction of transcription factor binding sites using an integrated model

Kyoung-Jae Won, Bing Ren, Wei Wang Genome Biology 2010, 11:R7 (22 January 2010)

A new approach for genome-wide transcription factor binding site prediction is presented that integrates sequence and chromatin modification data.

Research   Open Access

ModuleDigger: an itemset mining framework for the detection of cis-regulatory modules

Hong Sun, Tijl De Bie, Valerie Storms, Qiang Fu, Thomas Dhollander, Karen Lemmens, Annemieke Verstuyf, Bart De Moor, Kathleen Marchal BMC Bioinformatics 2009, 10(Suppl 1):S30 (30 January 2009)