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Characteristics of Sme efflux transporters in S. maltophilia K279a |
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| Systematic ID |
Name |
Known or putative regulation mechanism |
Closest match to a known antimicrobial efflux protein |
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| Smlt4474-4476 |
SmeABC |
Two component regulator (SmeSR, Smlt4477-8) |
S. maltophilia SmeABC [20] |
| Smlt4070-4072 |
SmeDEF |
Tet-R type (SmeT, Smlt4073) |
S. maltophilia SmeDEF [17,22] |
| Smlt1829-1833 |
SmeVWX |
LysR type (Smlt1827) |
51%, 56% and 48% amino acid identity, respectively, to P. aeruginosa MexEF-OprN [64] |
| Smlt2201-2202 |
SmeYZ |
Two component regulator (Smlt2199-30) |
44% and 59% amino acid identity, respectively, to AdeAB of A. baumanii [65] |
| Smlt3170-3171 |
SmeGH |
TetR type (Smlt3169) |
39% and 49% amino acid identity, respectively, to AcrAB of M. morganii [66] |
| Smlt3788-3787 |
SmeMN |
? |
<30% identity to other known antimicrobial efflux proteins |
| Smlt3925-3924 |
SmeOP |
TetR type (Smlt3926) |
<30% identity to other known antimicrobial efflux proteins |
| Smlt4279/4281 |
SmeIJK |
? |
41%, 50% and 44% amino acid identity, respectively, to MtdABC of E. coli [25] |
Crossman et al. Genome Biology 2008 9:R74 doi:10.1186/gb-2008-9-4-r74 |
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