|
MICs of a variety of antimicrobials against S. maltophilia K279a and derivatives lacking specific functional RND efflux pump genes |
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| Gent |
Kan |
Ami |
Tob |
Ery |
Chor |
Mero |
Imi |
Azt |
Ctz |
Pip |
Tet |
Min |
Trim |
Sul |
Cipro |
Levo |
Nor |
|
|
|
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| K279a |
16 |
256 |
64 |
32 |
>1,024 |
6 |
32 |
256 |
256 |
8 |
64 |
16 |
0.25 |
32 |
64 |
2 |
4 |
32 |
| smeJ |
8 |
256 |
32 |
32 |
>1,024 |
6 |
32 |
256 |
512 |
8 |
64 |
8 |
0.125 |
32 |
64 |
1 |
4 |
32 |
| smeK |
8 |
256 |
32 |
32 |
>1,024 |
6 |
32 |
256 |
512 |
8 |
64 |
8 |
0.125 |
32 |
64 |
1 |
4 |
32 |
| smeJK |
8 |
256 |
32 |
32 |
>1,024 |
6 |
32 |
256 |
512 |
8 |
64 |
8 |
0.125 |
32 |
64 |
1 |
4 |
32 |
| smeZ |
1 |
128 |
32 |
16 |
>1,024 |
6 |
32 |
256 |
512 |
8 |
64 |
16 |
0.25 |
32 |
64 |
2 |
4 |
32 |
|
Gent, gentamicin, Kan, kanamycin; Ami, amikacin; Tob, tobramycin; Ery, erythromycin; Chor, chloramphenicol; Mero, meropenem; Imi, imipenem; Azt, aztreonam; Ctz, ceftazidime; Pip, piperacillin; Tet, tetracycline; Min, minocycline; Trim, trimpethoprim; Sul, sulphamethoxazole; Cipro, ciprofloxacin; Levo, levofloxacin; Nor, norfloxacin. Entries in bold indicate changes of the MIC in the mutants compared to wild type K279a. The units used are in mg/L | ||||||||||||||||||
Crossman et al. Genome Biology 2008 9:R74 doi:10.1186/gb-2008-9-4-r74 |
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